Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAT1 | P18440 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047611 | 1.00 | KDM4E (0.51) | KDM4ECYP1A2CYP2C19ALDH1A1RAB9A | |
| SCHEMBL9046784 | 0.81 | KDM4E (0.34) | KDM4ECYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL9046794 | 0.81 | KDM4E (0.34) | KDM4ECYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL9047786 | 0.79 | DYRK2 (0.56) | ALDH1A1MAPTACHEHDAC1 | |
| SCHEMBL9047790 | 0.79 | DYRK2 (0.56) | ALDH1A1MAPTACHEHDAC1 | |
| SCHEMBL9046118 | 0.79 | IKBKB (0.58) | ALDH1A1RAB9AMAPTNPC1ACHE | |
| SCHEMBL9046126 | 0.79 | IKBKB (0.58) | ALDH1A1RAB9AMAPTNPC1ACHE | |
| SCHEMBL9050279 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1MAPTNPC1ACHE | |
| SCHEMBL9047693 | 0.79 | IKBKB (0.33) | KDM4ECYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL9047712 | 0.79 | IKBKB (0.33) | KDM4ECYP1A2CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |