Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047790 | 1.00 | DYRK2 (0.56) | DYRK2ACHEXDHPIM1MAPT | |
| SCHEMBL9047791 | 0.81 | MEN1 (0.41) | DYRK2ALDH1A1 | |
| SCHEMBL9047779 | 0.81 | MEN1 (0.41) | DYRK2ALDH1A1 | |
| SCHEMBL9046126 | 0.79 | IKBKB (0.58) | DYRK2ACHEMAPTEGFRALDH1A1 | |
| SCHEMBL9046118 | 0.79 | IKBKB (0.58) | DYRK2ACHEMAPTEGFRALDH1A1 | |
| SCHEMBL9047611 | 0.79 | KDM4E (0.51) | ACHEMAPTHDAC1ALDH1A1 | |
| SCHEMBL9047619 | 0.79 | KDM4E (0.51) | ACHEMAPTHDAC1ALDH1A1 | |
| SCHEMBL10730964 | 0.78 | MAPT (0.56) | ACHEXDHMAPTHTTNPSR1 | |
| SCHEMBL9740855 | 0.77 | ALDH1A1 (0.49) | ACHEPIM1MAPTHTTNPSR1 | |
| SCHEMBL7328466 | 0.77 | ALDH1A1 (0.49) | ACHEPIM1MAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |