Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 2/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047693 | 1.00 | IKBKB (0.33) | IKBKBHSD11B1FAAHMGLLKDM4E | |
| SCHEMBL9047619 | 0.79 | KDM4E (0.51) | IKBKBHSD11B1KDM4EMAPTALDH1A1 | |
| SCHEMBL9047611 | 0.79 | KDM4E (0.51) | IKBKBHSD11B1KDM4EMAPTALDH1A1 | |
| SCHEMBL9047790 | 0.76 | DYRK2 (0.56) | MAPTALDH1A1DYRK2 | |
| SCHEMBL9046126 | 0.76 | IKBKB (0.58) | IKBKBMAPTALDH1A1DYRK2RAF1 | |
| SCHEMBL9046118 | 0.76 | IKBKB (0.58) | IKBKBMAPTALDH1A1DYRK2RAF1 | |
| SCHEMBL9047786 | 0.76 | DYRK2 (0.56) | MAPTALDH1A1DYRK2 | |
| SCHEMBL9050261 | 0.75 | KDM4E (0.57) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL9050279 | 0.75 | KDM4E (0.57) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL9047846 | 0.75 | HDAC1 (0.46) | KDM4EMAPTALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |