Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropylbenzene SCHEMBL1416132 | 0.91 | ALDH1A1 (0.44) | ALDH1A1LMNATDP1MAPTKDM4E | |
| Isopropylbenzene SCHEMBL27353084 | 0.91 | ALDH1A1 (0.57) | ALDH1A1LMNATDP1MAPTKDM4E | |
| Isopropylbenzene SCHEMBL894807 | 0.91 | ALDH1A1 (0.57) | ALDH1A1LMNATDP1MAPTKDM4E | |
| Isopropylbenzene SCHEMBL8330328 | 0.88 | ALDH1A1 (0.55) | ALDH1A1LMNATDP1MAPTKDM4E | |
| Isopropylbenzene SCHEMBL27513961 | 0.88 | ALDH1A1 (0.55) | ALDH1A1LMNATDP1MAPTKDM4E | |
| Isopropylbenzene SCHEMBL719550 | 0.88 | ALDH1A1 (0.55) | ALDH1A1LMNATDP1MAPTKDM4E | |
| Isopropylbenzene SCHEMBL2013493 | 0.88 | ALDH1A1 (0.55) | ALDH1A1LMNATDP1MAPTKDM4E | |
| Isopropylbenzene SCHEMBL8330332 | 0.88 | ALDH1A1 (0.55) | ALDH1A1LMNATDP1MAPTKDM4E | |
| Isopropylbenzene SCHEMBL20448550 | 0.86 | SRC (0.52) | ALDH1A1LMNATDP1MAPTKDM4E | |
| Isopropylbenzene SCHEMBL27343723 | 0.86 | ALDH1A1 (0.48) | ALDH1A1LMNATDP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510526-B1 | Use of sulfonamides as drug and new sulfonamides | HOFFMANN LA ROCHE (CH) | 1996-12-04 | — | — | EP | disclosed |
| EP-0510526-A1 | Use of sulfonamides as drug and new sulfonamides | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1992-10-28 | — | — | EP | disclosed |
| EP-0221344-B1 | SULPHONYL-PHENYL ALKYL AMINES, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0221344-A1 | Sulphonyl-phenyl alkyl amines, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1987-05-13 | — | — | EP | disclosed |
| US-3932419-A | QUINOLINE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |