Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Isopropylbenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropylbenzene SCHEMBL894807 | 0.98 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| Isopropylbenzene SCHEMBL27353084 | 0.98 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| Isopropylbenzene SCHEMBL8330328 | 0.95 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| Isopropylbenzene SCHEMBL2013493 | 0.95 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| Isopropylbenzene SCHEMBL8330332 | 0.95 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| Isopropylbenzene SCHEMBL8555471 | 0.91 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| Isopropylbenzene SCHEMBL27513961 | 0.91 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| Isopropylbenzene SCHEMBL20448550 | 0.88 | SRC (0.52) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| Isopropylbenzene SCHEMBL27343723 | 0.88 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| Isopropylbenzene SCHEMBL9047739 | 0.88 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998859-B2 | Surface preparation process for damascene copper deposition | ENTHONE INC. (US) | 2011-08-16 | — | — | US | claimed |
| US-20100075496-A1 | SURFACE PREPARATION PROCESS FOR DAMASCENE COPPER DEPOSITION | ENTHONE INC. (US) | 2010-03-25 | — | — | US | claimed |
| US-7592296-B2 | Conveyor track or container lubricant compositions | JOHNSONDIVERSEY, INC. (US) | 2009-09-22 | — | — | US | claimed |
| EP-1778825-A1 | CONVEYOR TRACK OR CONTAINER LUBRICANT COMPOSITIONS | JohnsonDiversey Inc. (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2007002070-A2 | ZINC-NICKEL ALLOY ELECTROPLATING SYSTEM | PAVCO, INC. (US) | 2007-01-04 | — | — | WO | claimed |
| US-20060283715-A1 | ZINC-NICKEL ALLOY ELECTROPLATING SYSTEM | PAVCO, INC. | 2006-12-21 | — | — | US | claimed |
| WO-2006017503-A1 | CONVEYOR TRACK OR CONTAINER LUBRICANT COMPOSITIONS | JOHNSONDIVERSEY, INC. (US) | 2006-02-16 | — | — | WO | claimed |
| US-20060030497-A1 | Conveyor track or container lubricant compositions | DIVERSEY, INC. (FORMERLY KNOWN AS JOHNSONDIVERSEY, INC.) | 2006-02-09 | — | — | US | claimed |
| US-20250270475-A1 | FABRIC AND HOME CARE COMPOSITION COMPRISING SURFACTANT AND A POLYESTER | THE PROCTER & GAMBLE COMPANY | 2025-08-28 | — | — | US | disclosed |
| US-12203056-B2 | Sulfoperoxycarboxylic acids, their preparation and methods of use as bleaching and antimicrobial agents | ECOLAB USA INC. (US) | 2025-01-21 | — | — | US | disclosed |
| US-20240158723-A1 | SULFOPEROXYCARBOXYLIC ACIDS, THEIR PREPARATION AND METHODS OF USE AS BLEACHING AND ANTIMICROBIAL AGENTS | ECOLAB USA INC. | 2024-05-16 | — | — | US | disclosed |
| EP-4321604-A1 | A FABRIC AND HOME CARE COMPOSITION COMPRISING SURFACTANT AND A POLYESTER | The Procter & Gamble Company (US) | 2024-02-14 | — | — | EP | disclosed |
| US-11827867-B2 | Sulfoperoxycarboxylic acids, their preparation and methods of use as bleaching and antimicrobial agents | ECOLAB USA INC. (US) | 2023-11-28 | — | — | US | disclosed |
| CN-113163754-B | Stable iodine-containing antimicrobial teat dip compositions | 埃科莱布美国股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| WO-1998053036-A1 | ALKYLPOLYGLUCOSIDES CONTAINING DISINFECTANT COMPOSITIONS ACTIVE AGAINST PSEUDOMONAS MICROORGANISM | NOVAPHARM RESEARCH (AUSTRALIA) PTY. LIMITED (AU) | 1998-11-26 | — | — | WO | disclosed |
| CN-1169749-A | Detergent compositions containing enduring perfume | PROCTER & GAMBLE (US) | 1998-01-07 | — | — | CN | disclosed |
| WO-1997031094-A1 | DETERGENT COMPOSITIONS CONTAINING ENDURING PERFUME | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |
| EP-0787177-A1 | DETERGENT COMPOSITIONS CONTAINING ENDURING PERFUME | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996012786-A1 | DETERGENT COMPOSITIONS CONTAINING ENDURING PERFUME | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |
| CN-1038302-A | The heavy duty liquid laundry detergents that contains negatively charged ion and nonionogenic tenside, washing assistant and proteolytic enzyme | PROCTER & GAMBLE (US) | 1989-12-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827867-B2 | Sulfoperoxycarboxylic acids, their preparation and methods of use as bleaching and antimicrobial agents | GPX4, PRDX1, PRDX4 | ADRA2A 4376/4885ADRA2C 3425/4885ALDH1A1 562/4885 |
| US-12203056-B2 | Sulfoperoxycarboxylic acids, their preparation and methods of use as bleaching and antimicrobial agents | GPX4, PRDX1, PRDX4 | ADRA2A 4376/4885ADRA2C 3425/4885ALDH1A1 562/4885 |
| US-20240158723-A1 | SULFOPEROXYCARBOXYLIC ACIDS, THEIR PREPARATION AND METHODS OF USE AS BLEACHING AND ANTIMICROBIAL AGENTS | GPX4, PRDX1, PRDX4 | ADRA2A 4376/4885ADRA2C 3425/4885ALDH1A1 562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.