SCHEMBL9047778

SCHEMBL9047778

C1CC[C@H]2C[N]CC[C@H]2C1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7853217 1.00 ALDH1A1 (0.47) ALDH1A1NOS3NOS1NOS2
SCHEMBL3242094 1.00 ALDH1A1 (0.47) ALDH1A1NOS3NOS1NOS2
SCHEMBL23203 1.00 ALDH1A1 (0.47) ALDH1A1NOS3NOS1NOS2
SCHEMBL1775895 1.00 ALDH1A1 (0.47) ALDH1A1NOS3NOS1NOS2
SCHEMBL1366434 0.97 ALDH1A1 (0.44) ALDH1A1NOS3NOS1NOS2
SCHEMBL11221870 0.97 ALDH1A1 (0.44) ALDH1A1NOS3NOS1NOS2
SCHEMBL7853346 0.97 ALDH1A1 (0.44) ALDH1A1NOS3NOS1NOS2
SCHEMBL7856162 0.97 ALDH1A1 (0.44) ALDH1A1NOS3NOS1NOS2
SCHEMBL3975125 0.94
SCHEMBL9047801 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0507534-B1 Succinic acid compounds KISSEI PHARMACEUTICAL (JP) 1996-02-28 EP disclosed
US-5202335-A Hypoglycemic, antidiabetic agents KISSEI PHARMACEUTICAL CO., LTD. (JP) 1993-04-13 US disclosed
EP-0507534-A1 Succinic acid compounds KISSEI PHARMACEUTICAL CO., LTD. (JP) 1992-10-07 EP disclosed