Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853217 | 1.00 | ALDH1A1 (0.47) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL9047778 | 1.00 | ALDH1A1 (0.47) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL3242094 | 1.00 | ALDH1A1 (0.47) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL1775895 | 1.00 | ALDH1A1 (0.47) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL1366434 | 0.97 | ALDH1A1 (0.44) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL11221870 | 0.97 | ALDH1A1 (0.44) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL7853346 | 0.97 | ALDH1A1 (0.44) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL7856162 | 0.97 | ALDH1A1 (0.44) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL3975125 | 0.94 | — | — | |
| SCHEMBL9047801 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 599 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603508-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2019-03-13 | — | — | EP | claimed |
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2019-03-07 | — | — | US | claimed |
| US-9924721-B2 | Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-27 | — | — | US | claimed |
| EP-3013821-B1 | PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2018-03-14 | — | — | EP | claimed |
| US-20160198713-A1 | Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-14 | — | — | US | claimed |
| EP-3039023-A1 | MALONIC ESTER DERIVATIVES OF HETEROARYLPIPERIDINES AND -PIPERAZINES AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-07-06 | — | — | EP | claimed |
| US-20160135461-A1 | PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-05-19 | — | — | US | claimed |
| EP-3013821-A1 | PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-05-04 | — | — | EP | claimed |
| US-9328107-B2 | Primary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2016-05-03 | — | — | US | claimed |
| US-9006266-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | claimed |
| WO-1988006885-A1 | PHOSPHOLIPASE A2 INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-09-22 | — | — | WO | claimed |
| US-4735959-A | HYPOGLYCEMIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1988-04-05 | — | — | US | claimed |
| EP-0103465-B1 | 20-AMINO MACROLIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1986-09-10 | — | — | EP | claimed |
| EP-0063826-B1 | 2-AMINO-BENZOIC-ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES OR INTERMEDIATES | Dr. Karl Thomae GmbH (DE) | 1984-12-05 | — | — | EP | claimed |
| EP-0124216-A1 | C-20- and C-23-modified macrolide derivatives | ELI LILLY AND COMPANY (US) | 1984-11-07 | — | — | EP | claimed |
| US-4468511-A | C-20- And C-23-Modified macrolide derivatives | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | claimed |
| EP-0103465-A1 | 20-Amino macrolide derivatives | ELI LILLY AND COMPANY (US) | 1984-03-21 | — | — | EP | claimed |
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | claimed |
| EP-0063826-A2 | 2-Amino-benzoic-acid derivatives, their preparation and their use as medicines or intermediates | Dr. Karl Thomae GmbH (DE) | 1982-11-03 | — | — | EP | claimed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160198713-A1 | Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides | ME1, CYP1A1, CYP1A2 | ALDH1A1 383/4885NOS3 1428/4885NOS1 841/4885 |
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | HTR5A, HTR2A, HTR1A | ALDH1A1 953/4885NOS3 178/4885NOS1 125/4885 |
| US-20160135461-A1 | PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | CYP1A1, PRXL2A, Q6ZSR9 | ALDH1A1 120/4885NOS3 129/4885NOS1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.