Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047791 | 1.00 | MEN1 (0.41) | MEN1ALDH1A1KMT2ATDP1CYP1A2 | |
| SCHEMBL9047790 | 0.81 | DYRK2 (0.56) | ALDH1A1DYRK2 | |
| SCHEMBL9047786 | 0.81 | DYRK2 (0.56) | ALDH1A1DYRK2 | |
| SCHEMBL980510 | 0.79 | MAOB (0.43) | MEN1ALDH1A1KMT2ATDP1CYP1A2 | |
| SCHEMBL980512 | 0.79 | MAOB (0.43) | MEN1ALDH1A1KMT2ATDP1CYP1A2 | |
| SCHEMBL9046794 | 0.79 | KDM4E (0.34) | MEN1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9047782 | 0.75 | AKR1C3 (0.50) | CYP1A2MAOAMAOB | |
| SCHEMBL9047523 | 0.75 | AKR1C3 (0.50) | CYP1A2MAOAMAOB | |
| SCHEMBL9048733 | 0.75 | CA12 (0.41) | ALDH1A1CYP1A2CYP3A4CYP2C19MAOB | |
| SCHEMBL9048726 | 0.75 | CA12 (0.41) | ALDH1A1CYP1A2CYP3A4CYP2C19MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |