Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048726 | 1.00 | CA12 (0.41) | CA12CA9KDM4EALDH1A1MAPT | |
| SCHEMBL9050261 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL9050279 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL9046794 | 0.78 | KDM4E (0.34) | KDM4EALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL10335357 | 0.77 | MAPT (0.61) | KDM4EALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL9123520 | 0.77 | MAPT (0.61) | KDM4EALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL17899552 | 0.75 | MAPT (0.56) | KDM4EALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL9740375 | 0.75 | ATM (0.61) | KDM4EALDH1A1MAPTMAOBMIF | |
| SCHEMBL9740370 | 0.75 | ATM (0.61) | KDM4EALDH1A1MAPTMAOBMIF | |
| SCHEMBL9047779 | 0.75 | MEN1 (0.41) | ALDH1A1MAOBCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |