Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049366 | 0.93 | HRH4 (0.35) | HRH3HRH4 | |
| Hydrochloric Acid SCHEMBL9046305 | 0.92 | HRH4 (0.34) | HRH3HRH4 | |
| SCHEMBL9049747 | 0.86 | HRH4 (0.38) | HRH3HRH4 | |
| SCHEMBL9048002 | 0.85 | HRH4 (0.35) | HRH3HRH4 | |
| SCHEMBL9045698 | 0.75 | MEN1 (0.32) | — | |
| Fumaric Acid SCHEMBL9048941 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL9050368 | 0.73 | DRD2 (0.39) | HRH3 | |
| Fumaric Acid SCHEMBL9048324 | 0.73 | GFER (0.32) | — | |
| SCHEMBL9048189 | 0.72 | — | — | |
| SCHEMBL4452676 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749966-A1 | 5-HT 3 RECEPTOR AGONIST, NOVEL THIAZOLE DERIVATIVE, AND INTERMEDIATE THEREFOR | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |