Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749899 | 0.88 | CES2 (0.47) | SRCCES2CES1ACP3SRD5A2 | |
| SCHEMBL7934481 | 0.84 | AKR1C3 (0.47) | CES2CES1ACP3AKR1C3AKR1C2 | |
| SCHEMBL3130953 | 0.83 | CES2 (0.53) | CES2CES1ACP3SRD5A2AKR1C3 | |
| SCHEMBL6809652 | 0.81 | MMP8 (0.48) | CES2CES1AKR1C3AKR1C2EPHX2 | |
| SCHEMBL504285 | 0.81 | CES2 (0.67) | CES2CES1ACP3SRD5A2AKR1C3 | |
| SCHEMBL504284 | 0.81 | CES2 (0.67) | CES2CES1ACP3SRD5A2AKR1C3 | |
| SCHEMBL5860711 | 0.81 | CES2 (0.52) | CES2CES1ACP3SRD5A2AKR1C3 | |
| SCHEMBL4634324 | 0.81 | CES2 (0.67) | CES2CES1ACP3SRD5A2AKR1C3 | |
| SCHEMBL271988 | 0.81 | SRC (0.78) | SRCCES2CES1AKR1C3AKR1C2 | |
| SCHEMBL5225725 | 0.79 | GRM8 (0.50) | CES2CES1ACP3SRD5A2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1335831-A | Polymerizable halogenated vinyl ethers | ALLIED SIGNAL INC (US) | 2002-02-13 | — | — | CN | disclosed |
| EP-0510526-B1 | Use of sulfonamides as drug and new sulfonamides | HOFFMANN LA ROCHE (CH) | 1996-12-04 | — | — | EP | disclosed |
| EP-0510526-A1 | Use of sulfonamides as drug and new sulfonamides | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1992-10-28 | — | — | EP | disclosed |