Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 6/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427077 | 0.94 | SIGMAR1 (0.44) | PTGIRSIGMAR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9427323 | 0.89 | SIGMAR1 (0.40) | PTGIRSIGMAR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9048458 | 0.89 | PTGIR (0.45) | PTGIRSIGMAR1ALDH1A1HTTMEN1 | |
| SCHEMBL9048482 | 0.85 | PTGIR (0.48) | PTGIRSIGMAR1KDM4C | |
| SCHEMBL9048041 | 0.83 | PTGIR (0.47) | PTGIRSIGMAR1KDM4C | |
| SCHEMBL9567967 | 0.81 | TRPV1 (0.44) | ALDH1A1HTTKDM4C | |
| SCHEMBL9048020 | 0.81 | PTGIR (0.67) | PTGIRSIGMAR1KDM4C | |
| SCHEMBL9048669 | 0.80 | MEN1 (0.42) | ALDH1A1HTTNPSR1SLC6A5MEN1 | |
| SCHEMBL9048016 | 0.80 | PTGIR (0.48) | PTGIRSIGMAR1KDM4C | |
| SCHEMBL9049779 | 0.80 | PTGIR (0.44) | PTGIRSIGMAR1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |