Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048014 | 0.89 | PTGIR (0.43) | PTGIRALDH1A1HTTLTB4R2SIGMAR1 | |
| SCHEMBL9048482 | 0.86 | PTGIR (0.48) | PTGIRSIGMAR1 | |
| SCHEMBL9048041 | 0.85 | PTGIR (0.47) | PTGIRSIGMAR1 | |
| SCHEMBL9427077 | 0.83 | SIGMAR1 (0.44) | PTGIRALDH1A1NPC1HTTLTB4R2 | |
| SCHEMBL9048429 | 0.82 | PTGIR (0.69) | PTGIRLTB4R2SIGMAR1 | |
| SCHEMBL9049779 | 0.81 | PTGIR (0.44) | PTGIRSIGMAR1 | |
| SCHEMBL9427485 | 0.81 | PTGIR (0.45) | PTGIRSIGMAR1 | |
| SCHEMBL9427323 | 0.80 | SIGMAR1 (0.40) | PTGIRALDH1A1HTTSIGMAR1MEN1 | |
| SCHEMBL9427205 | 0.80 | PTGIR (0.69) | PTGIRSIGMAR1 | |
| SCHEMBL9048752 | 0.79 | PTGIR (0.42) | PTGIRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |