Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.59 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889158 | 0.89 | ERN1 (0.71) | ERN1TRIM24TRIM33TYRCDK1 | |
| SCHEMBL28356776 | 0.86 | TYR (0.59) | ERN1SOS1TRIM24TRIM33TYR | |
| SCHEMBL3887594 | 0.86 | ERN1 (0.62) | ERN1TRIM24TRIM33TYRCDK1 | |
| SCHEMBL6093640 | 0.84 | ERN1 (0.61) | ERN1TRIM24TRIM33TYRCDK1 | |
| SCHEMBL12952823 | 0.82 | ERN1 (0.54) | ERN1TRIM24TRIM33TYRCDK1 | |
| SCHEMBL9048974 | 0.80 | ERN1 (0.40) | ERN1SOS1TYRALDH1A1L3MBTL1 | |
| SCHEMBL9048969 | 0.80 | ERN1 (0.40) | ERN1SOS1TYRALDH1A1L3MBTL1 | |
| SCHEMBL117649 | 0.79 | ERN1 (0.57) | ERN1TRIM24TRIM33CDK1 | |
| SCHEMBL29694520 | 0.79 | ERN1 (0.57) | ERN1TRIM24TRIM33CDK1 | |
| SCHEMBL9729990 | 0.79 | ERN1 (0.58) | ERN1TRIM24TRIM33TYRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110845345-B | Aromatic diamine monomer and preparation method thereof | 中国科学院长春应用化学研究所 | 2021-11-09 | — | — | CN | disclosed |
| CN-110791833-B | Polyimide fiber and preparation method thereof | 中国科学院长春应用化学研究所 | 2021-02-05 | — | — | CN | disclosed |
| CN-110845345-A | Aromatic diamine monomer and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-02-28 | — | — | CN | disclosed |
| CN-110791833-A | Polyimide fiber and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-02-14 | — | — | CN | disclosed |
| EP-0540673-B1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1996-10-16 | — | — | EP | disclosed |
| US-5559144-A | LIPOXYGENASE INHIBITORS, INHIBITORS OF BIOSYNTHESIS OF LEUKOTRIENES | ABBOTT LABORATORIES (US) | 1996-09-24 | — | — | US | disclosed |
| US-5476873-A | Inhibit biosynthesis of leukotrienes | ABBOTT LABORATORIES (US) | 1995-12-19 | — | — | US | disclosed |
| EP-0540673-A4 | — | — | 1994-04-27 | — | — | EP | disclosed |
| EP-0540673-A1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY. | ABBOTT LAB (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001682-A1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1992-02-06 | — | — | WO | disclosed |