Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046613 | 0.84 | ALOX5 (0.43) | ACACBALOX5EPHX2MMP2MMP9 | |
| SCHEMBL9048114 | 0.83 | ALOX5 (0.43) | ACACBALOX5EPHX2 | |
| SCHEMBL9047965 | 0.83 | ALOX5 (0.43) | ACACBALOX5EPHX2 | |
| SCHEMBL9047863 | 0.83 | ALOX5 (0.59) | ACACBALOX5EPHX2 | |
| SCHEMBL9047354 | 0.83 | ALOX5 (0.43) | ACACBALOX5EPHX2MMP2MMP9 | |
| SCHEMBL9048409 | 0.82 | ALOX5 (0.53) | ACACBALOX5EPHX2 | |
| SCHEMBL9370185 | 0.72 | ALOX5 (0.57) | ACACBALOX5EPHX2 | |
| SCHEMBL8948277 | 0.70 | ALOX5 (0.78) | ACACBALOX5EPHX2 | |
| SCHEMBL9047292 | 0.66 | ALOX5 (0.64) | ACACBALOX5EPHX2 | |
| SCHEMBL9473424 | 0.66 | FFAR1 (0.50) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540673-B1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1996-10-16 | — | — | EP | disclosed |
| US-5559144-A | LIPOXYGENASE INHIBITORS, INHIBITORS OF BIOSYNTHESIS OF LEUKOTRIENES | ABBOTT LABORATORIES (US) | 1996-09-24 | — | — | US | disclosed |
| US-5476873-A | Inhibit biosynthesis of leukotrienes | ABBOTT LABORATORIES (US) | 1995-12-19 | — | — | US | disclosed |