Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046613 | 0.86 | ALOX5 (0.43) | ALOX5EPHX2FFAR1ACACBACACA | |
| SCHEMBL9047965 | 0.85 | ALOX5 (0.43) | ALOX5EPHX2FFAR1ACACBACACA | |
| SCHEMBL9047354 | 0.85 | ALOX5 (0.43) | ALOX5EPHX2PTGESACACB | |
| SCHEMBL9048114 | 0.85 | ALOX5 (0.43) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL9048100 | 0.82 | ACACB (0.47) | ALOX5EPHX2ACACB | |
| SCHEMBL9048674 | 0.81 | ALOX5 (0.71) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL9473424 | 0.79 | FFAR1 (0.50) | ALOX5FFAR1 | |
| SCHEMBL9047172 | 0.76 | ALOX5 (0.59) | ALOX5EPHX2PTGESFFAR1ACACB | |
| SCHEMBL8965207 | 0.75 | ACACB (0.48) | ALOX5EPHX2FFAR1ACACB | |
| SCHEMBL9046903 | 0.75 | ALOX5 (0.74) | ALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540673-B1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1996-10-16 | — | — | EP | disclosed |
| US-5559144-A | LIPOXYGENASE INHIBITORS, INHIBITORS OF BIOSYNTHESIS OF LEUKOTRIENES | ABBOTT LABORATORIES (US) | 1996-09-24 | — | — | US | disclosed |