Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | SLC16A3 | O15427 | 10/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615957 | 0.86 | LMNA (0.41) | FOLH1SLC16A3ALDH1A1 | |
| SCHEMBL31474045 | 0.83 | FOLH1 (0.70) | FOLH1SLC16A3TSHRALDH1A1ALOX15 | |
| SCHEMBL729909 | 0.83 | FOLH1 (0.70) | FOLH1SLC16A3TSHRALDH1A1ALOX15 | |
| SCHEMBL9345842 | 0.81 | FOLH1 (0.68) | FOLH1SLC16A3TSHRALDH1A1ALOX15 | |
| SCHEMBL9045795 | 0.81 | HTT (0.37) | FOLH1SLC16A3ALDH1A1 | |
| SCHEMBL9044047 | 0.81 | CLCN2 (0.43) | FOLH1SLC16A3ALDH1A1ALOX15CLCN2 | |
| SCHEMBL165530 | 0.80 | FOLH1 (0.61) | FOLH1SLC16A3TSHRALDH1A1ALOX15 | |
| SCHEMBL30365583 | 0.79 | FOLH1 (0.76) | FOLH1SLC16A3TSHRALDH1A1ALOX15 | |
| SCHEMBL70392 | 0.79 | FOLH1 (0.76) | FOLH1SLC16A3TSHRALDH1A1ALOX15 | |
| Bromide SCHEMBL3174157 | 0.79 | FOLH1 (0.59) | FOLH1SLC16A3TSHRALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |