Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 3/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266778 | 0.83 | TSHR (0.41) | HTTCES1MLYCDMAPK1ALDH1A1 | |
| SCHEMBL8615957 | 0.81 | LMNA (0.41) | HTTFOLH1ALDH1A1LMNASLC16A3 | |
| SCHEMBL9048128 | 0.81 | FOLH1 (0.56) | FOLH1ALDH1A1SLC16A3 | |
| SCHEMBL9624253 | 0.80 | LIPG (0.50) | MLYCDALDH1A1LMNAFAAH | |
| SCHEMBL10341072 | 0.80 | LIPG (0.50) | MLYCDALDH1A1LMNAFAAH | |
| SCHEMBL9637940 | 0.80 | LIPG (0.50) | MLYCDALDH1A1LMNAFAAH | |
| SCHEMBL9747292 | 0.79 | CES1 (0.42) | HTTCES1MLYCDFOLH1MAPK1 | |
| SCHEMBL10717585 | 0.77 | CES1 (0.47) | HTTCES1MLYCDMAPK1LMNA | |
| SCHEMBL32665929 | 0.77 | CES1 (0.47) | HTTCES1MLYCDMAPK1LMNA | |
| SCHEMBL8957447 | 0.73 | HPGD (0.47) | HTTCES1FOLH1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |