Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048865 | 0.75 | ALOX5 (0.49) | ALOX5EPHX2 | |
| SCHEMBL9048193 | 0.74 | ALOX5 (0.50) | ALOX5EPHX2 | |
| SCHEMBL9046357 | 0.74 | ALOX5 (0.65) | ALOX5EPHX2 | |
| SCHEMBL8310117 | 0.72 | ALOX5 (0.63) | ALOX5EPHX2 | |
| SCHEMBL2108326 | 0.70 | ALOX5 (0.69) | ALOX5EPHX2HPGD | |
| SCHEMBL2108330 | 0.70 | ALOX5 (0.69) | ALOX5EPHX2HPGD | |
| Atreleuton SCHEMBL2108309 | 0.70 | ALOX5 (1.00) | ALOX5EPHX2 | |
| Atreleuton SCHEMBL2107799 | 0.70 | ALOX5 (1.00) | ALOX5EPHX2 | |
| SCHEMBL8306465 | 0.70 | ALOX5 (0.63) | ALOX5EPHX2 | |
| Atreleuton SCHEMBL504818 | 0.70 | ALOX5 (1.00) | ALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540673-B1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1996-10-16 | — | — | EP | disclosed |