Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048196 | 0.75 | ALOX5 (0.54) | ALOX5EPHX2 | |
| SCHEMBL9046357 | 0.75 | ALOX5 (0.65) | ALOX5EPHX2 | |
| SCHEMBL9047626 | 0.71 | ALOX5 (0.44) | ALOX5EPHX2 | |
| SCHEMBL9048193 | 0.69 | ALOX5 (0.50) | ALOX5EPHX2 | |
| SCHEMBL9048880 | 0.68 | ALOX5 (0.52) | ALOX5EPHX2 | |
| SCHEMBL5148459 | 0.66 | APP (0.39) | — | |
| Atreleuton SCHEMBL2108309 | 0.66 | ALOX5 (1.00) | ALOX5EPHX2 | |
| SCHEMBL8310117 | 0.66 | ALOX5 (0.63) | ALOX5EPHX2 | |
| Atreleuton SCHEMBL2107799 | 0.66 | ALOX5 (1.00) | ALOX5EPHX2 | |
| SCHEMBL8306465 | 0.66 | ALOX5 (0.63) | ALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540673-B1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1996-10-16 | — | — | EP | disclosed |