Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049539 | 0.82 | ALDH1A1 (0.43) | CYP3A4DAOHRH4HRH3CYP1A2 | |
| SCHEMBL8661339 | 0.82 | ALDH1A1 (0.42) | CYP3A4CYP1A2ALDH1A1CYP2C9CYP2D6 | |
| SCHEMBL5935684 | 0.74 | ALDH1A1 (0.42) | ALDH1A1CYP2C9PDE7A | |
| SCHEMBL8660050 | 0.74 | ALDH1A1 (0.39) | CYP3A4CYP1A2ALDH1A1CYP2C9CYP2D6 | |
| SCHEMBL8660046 | 0.74 | ALDH1A1 (0.39) | CYP3A4CYP1A2ALDH1A1CYP2C9CYP2D6 | |
| SCHEMBL13103908 | 0.74 | ALDH1A1 (0.42) | ALDH1A1CYP2C9PDE7A | |
| SCHEMBL9052233 | 0.73 | ALDH1A1 (0.46) | DAOCYP1A2ALDH1A1CYP2C9CYP2D6 | |
| SCHEMBL7405579 | 0.73 | CYP1A2 (0.56) | DAOHRH4HRH3CYP1A2L3MBTL1 | |
| SCHEMBL9050747 | 0.70 | SMN1; SMN2 (0.55) | DAO | |
| SCHEMBL9048067 | 0.70 | CA12 (0.44) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660826-A4 | 5,5-DISUBSTITUTED HYDANTOINS. | SOUTHERN RES INST (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0660826-A1 | 5,5-DISUBSTITUTED HYDANTOINS | SOUTHERN RESEARCH INSTITUTE (US) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006775-A1 | 5,5-DISUBSTITUTED HYDANTOINS | SOUTHERN RESEARCH INSTITUTE (US) | 1994-03-31 | — | — | WO | disclosed |