Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 6/20 | 0.42 |
| ▸ | MMP2 | P08253 | 5/20 | 0.42 |
| ▸ | MMP8 | P22894 | 5/20 | 0.42 |
| ▸ | MMP13 | P45452 | 5/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661339 | 0.80 | ALDH1A1 (0.42) | SMN1; SMN2CRBNMAOAMAOBADAM17 | |
| Hydrochloric Acid SCHEMBL9053511 | 0.79 | GFER (0.34) | SMN1; SMN2NPSR1MAOAMAOB | |
| SCHEMBL9049539 | 0.78 | ALDH1A1 (0.43) | SMN1; SMN2LMNAMMP8MMP13DAO | |
| SCHEMBL9051430 | 0.77 | HTT (0.47) | SMN1; SMN2MAOAMAOBDAOBCHE | |
| SCHEMBL9048067 | 0.77 | CA12 (0.44) | LMNAGAA | |
| SCHEMBL11607926 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2NPSR1LMNAMMP9MMP2 | |
| SCHEMBL9046628 | 0.76 | CYP1A2 (0.50) | LMNAMMP8BCHEACHEIDO1 | |
| SCHEMBL5935684 | 0.75 | ALDH1A1 (0.42) | CRBNLMNAMMP9MMP2MMP8 | |
| SCHEMBL11604698 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2NPSR1LMNAMMP9MMP2 | |
| SCHEMBL8660046 | 0.72 | ALDH1A1 (0.39) | CRBNMAOAMAOBADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660826-A4 | 5,5-DISUBSTITUTED HYDANTOINS. | SOUTHERN RES INST (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0660826-A1 | 5,5-DISUBSTITUTED HYDANTOINS | SOUTHERN RESEARCH INSTITUTE (US) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006775-A1 | 5,5-DISUBSTITUTED HYDANTOINS | SOUTHERN RESEARCH INSTITUTE (US) | 1994-03-31 | — | — | WO | disclosed |