Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27668148 | 0.85 | ALDH1A1 (0.45) | ALDH1A1GBA1MEN1CHRM1KMT2A | |
| SCHEMBL6645562 | 0.85 | CYP2C19 (0.49) | ALDH1A1CYP2C19SIGMAR1CXCR4MEN1 | |
| SCHEMBL27610338 | 0.82 | KDM4E (0.43) | ALDH1A1LMNAHTR2AHTR2CHTR2B | |
| SCHEMBL7489800 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GBA1LMNASIGMAR1CXCR4 | |
| SCHEMBL27668212 | 0.79 | SOS1 (0.43) | ALDH1A1TDP1HTR2AHTR2CHTR2B | |
| SCHEMBL27551217 | 0.78 | TEC (0.36) | — | |
| SCHEMBL28248966 | 0.76 | HTR2A (0.35) | ALDH1A1LMNAMEN1KMT2AHTR2A | |
| SCHEMBL26523503 | 0.76 | CYP2D6 (0.45) | ALDH1A1LMNAMEN1KMT2ATDP1 | |
| SCHEMBL27573609 | 0.76 | LSS (0.45) | HRH3HTR2AHTR2CHTR2B | |
| SCHEMBL27634719 | 0.76 | SLC6A2 (0.40) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706517-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-04-17 | — | — | EP | disclosed |