Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 8/20 | 0.69 |
| ▸ | AKR1A1 | P14550 | 3/20 | 0.69 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056716 | 0.90 | AKR1B1 (0.78) | AKR1B1AKR1A1AKR1B10PTGDR2MEN1 | |
| SCHEMBL10488007 | 0.88 | AKR1B1 (0.85) | AKR1B1AKR1A1AKR1B10PTGDR2OPRM1 | |
| SCHEMBL9046869 | 0.87 | AKR1B1 (0.53) | AKR1B1AKR1A1AKR1B10OPRM1TRAP1 | |
| SCHEMBL9049383 | 0.87 | AKR1B1 (0.60) | AKR1B1AKR1A1AKR1B10PTGDR2TBXA2R | |
| Zenarestat SCHEMBL30583313 | 0.82 | AKR1B1 (1.00) | AKR1B1AKR1A1AKR1B10OPRM1TRAP1 | |
| Zenarestat SCHEMBL29688249 | 0.82 | AKR1B1 (1.00) | AKR1B1AKR1A1AKR1B10OPRM1TRAP1 | |
| Zenarestat SCHEMBL48959 | 0.82 | AKR1B1 (1.00) | AKR1B1AKR1A1AKR1B10OPRM1TRAP1 | |
| SCHEMBL9046879 | 0.81 | AKR1B1 (0.55) | AKR1B1AKR1A1AKR1B10TRAP1TBXA2R | |
| SCHEMBL9048160 | 0.77 | AKR1B1 (0.52) | AKR1B1AKR1A1AKR1B10TBXA2RMEN1 | |
| SCHEMBL9046143 | 0.77 | AKR1A1 (0.59) | AKR1B1AKR1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5234928-A | Inhibit platelet aggregation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0456835-A1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |