Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 5/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 3/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858641 | 0.86 | PTGIR (0.55) | TBXAS1PTGIRKDM4C | |
| SCHEMBL9046057 | 0.84 | TBXAS1 (0.39) | TBXAS1PTGIRKDM4CTAOK1KDM5B | |
| SCHEMBL9568012 | 0.83 | TAOK1 (0.35) | TBXAS1PTGIRKDM4CTAOK1KDM6B | |
| SCHEMBL9049505 | 0.82 | KDM4C (0.41) | TBXAS1PTGIRKDM4CTAOK1KDM5B | |
| SCHEMBL9047961 | 0.81 | TBXAS1 (0.40) | TBXAS1PTGIRKDM4CTAOK1KDM5B | |
| SCHEMBL9049155 | 0.78 | TBXAS1 (0.40) | TBXAS1PTGIRKDM4CTAOK1KDM5B | |
| SCHEMBL9048661 | 0.78 | TBXAS1 (0.40) | TBXAS1PTGIRKDM4CTAOK1KDM5B | |
| SCHEMBL9046069 | 0.77 | KDM4C (0.41) | TBXAS1PTGIRKDM4CKDM6BKDM5B | |
| SCHEMBL9048498 | 0.77 | TBXAS1 (0.41) | TBXAS1PTGIRKDM4CKDM6BKDM5B | |
| SCHEMBL9046403 | 0.76 | TBXAS1 (0.39) | TBXAS1PTGIRKDM4CTAOK1KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |