Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048468 | 0.83 | TBXAS1 (0.37) | TAOK1TBXAS1PTGIRKDM4CKDM5B | |
| SCHEMBL8858641 | 0.82 | PTGIR (0.55) | TBXAS1PTGIRKDM4C | |
| SCHEMBL9568066 | 0.74 | TBXAS1 (0.38) | TBXAS1PTGIRKDM4CKDM5BKDM5A | |
| SCHEMBL9047648 | 0.73 | PTGIR (0.40) | PTGIRALDH1A1TSHR | |
| SCHEMBL9567972 | 0.72 | TAOK1 (0.48) | TAOK1TBXAS1TAOK3POLBKDM4C | |
| SCHEMBL9568062 | 0.70 | TAOK1 (0.47) | TAOK1TBXAS1TAOK3POLBKDM4C | |
| SCHEMBL9568029 | 0.69 | TAOK1 (0.49) | TAOK1TBXAS1TAOK3POLBKDM4C | |
| SCHEMBL8858624 | 0.67 | TBXAS1 (0.59) | TBXAS1PTGIRKDM4C | |
| SCHEMBL9568050 | 0.66 | KDM4C (0.47) | TAOK1TBXAS1TAOK3POLBKDM4C | |
| SCHEMBL9567948 | 0.66 | PTGIR (0.35) | TBXAS1PTGIRKDM4CKDM5BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |