Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 9/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046402 | 0.91 | PTGIR (0.66) | PTGIRTBXAS1ALDH1A1KDM4CPTGDR2 | |
| SCHEMBL9048548 | 0.85 | PTGIR (0.51) | PTGIRTBXAS1ALDH1A1PTGDR2KDM4E | |
| SCHEMBL9427135 | 0.80 | PTGIR (0.69) | PTGIRTBXAS1ALDH1A1KDM4CPTGDR2 | |
| SCHEMBL9567996 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4CKDM4E | |
| SCHEMBL9427087 | 0.79 | PTGIR (0.81) | PTGIRTBXAS1KDM4CPTGDR2 | |
| SCHEMBL9050622 | 0.78 | PTGIR (0.62) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9048158 | 0.78 | PTGIR (0.62) | PTGIRTBXAS1KDM4CPTGDR2 | |
| SCHEMBL9047729 | 0.76 | PTGIR (0.66) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9049270 | 0.76 | PTGIR (0.59) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9050868 | 0.75 | PTGIR (0.64) | PTGIRTBXAS1ALDH1A1KDM4CPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |