Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 9/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050562 | 0.86 | NPSR1 (0.43) | PTGIRNPSR1ALDH1A1DRD4PDE5A | |
| SCHEMBL9048484 | 0.85 | PTGIR (0.56) | PTGIRTBXAS1PTGDR2ALDH1A1KDM4E | |
| SCHEMBL9046402 | 0.83 | PTGIR (0.66) | PTGIRTBXAS1PTGDR2ALDH1A1KDM4E | |
| SCHEMBL9050555 | 0.82 | NPSR1 (0.47) | NPSR1ALDH1A1KDM4EPDE5A | |
| SCHEMBL9046310 | 0.79 | PTGIR (0.61) | PTGIRTBXAS1PTGDR2DRD4 | |
| SCHEMBL9568017 | 0.78 | KCNQ2 (0.53) | NPSR1ALDH1A1KDM4EPDE5A | |
| SCHEMBL8858726 | 0.78 | PTGIR (0.56) | PTGIRTBXAS1PTGDR2ALDH1A1KDM4E | |
| SCHEMBL8858437 | 0.77 | PTGIR (0.56) | PTGIRTBXAS1PTGDR2DRD4 | |
| SCHEMBL8858415 | 0.77 | PTGIR (0.56) | PTGIRTBXAS1PTGDR2DRD4 | |
| SCHEMBL9046416 | 0.77 | PTGIR (0.70) | PTGIRTBXAS1PTGDR2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |