Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.60 |
| ▸ | MLNR | O43193 | 1/20 | 0.60 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.60 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | USP1 | O94782 | 1/20 | 0.60 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.60 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904836 | 0.86 | HTR2A (0.56) | USP2MEN1KMT2AALDH1A1HTR2A | |
| SCHEMBL5857440 | 0.85 | CYP2D6 (0.61) | USP2MEN1KMT2AALDH1A1HTR2A | |
| SCHEMBL904830 | 0.81 | DRD2 (0.60) | USP2MEN1KMT2AALDH1A1HTR2A | |
| SCHEMBL904848 | 0.81 | HTR2A (0.57) | USP2MEN1KMT2AALDH1A1HTR2A | |
| SCHEMBL17471517 | 0.79 | CYP2D6 (0.60) | USP2MEN1KMT2AALDH1A1HTR2A | |
| SCHEMBL5857451 | 0.78 | CYP2D6 (0.52) | USP2ALDH1A1HTR2ACYP2D6CYP3A4 | |
| SCHEMBL27589107 | 0.78 | USP2 (0.65) | USP2MEN1KMT2AALDH1A1HTR2A | |
| SCHEMBL10281564 | 0.77 | CYP2D6 (0.58) | USP2MEN1KMT2AALDH1A1HTR2A | |
| SCHEMBL5729319 | 0.77 | HTR2A (0.53) | USP2MEN1KMT2AALDH1A1HTR2A | |
| SCHEMBL904826 | 0.75 | HTR2A (0.58) | USP2MEN1KMT2AALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |