Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.57 |
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
| ▸ | HRH2 | P25021 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904828 | 0.86 | DRD3 (0.54) | DRD2SLC6A4OPRM1CYP2D6CACNA1F | |
| SCHEMBL5858616 | 0.85 | DRD2 (0.69) | DRD2SLC6A4OPRM1CYP2D6KMT2A | |
| SCHEMBL3294008 | 0.83 | DRD2 (0.62) | DRD2SLC6A4DRD1HTR2AHRH1 | |
| SCHEMBL904850 | 0.81 | USP2 (0.60) | DRD2SLC6A4OPRM1CYP2D6CACNA1F | |
| SCHEMBL5858744 | 0.78 | DRD2 (0.68) | DRD2SLC6A4OPRM1CYP2D6KMT2A | |
| SCHEMBL17471517 | 0.77 | CYP2D6 (0.60) | DRD2SLC6A4OPRM1CYP2D6CACNA1F | |
| SCHEMBL904848 | 0.77 | HTR2A (0.57) | DRD2SLC6A4OPRM1CYP2D6CACNA1F | |
| SCHEMBL5860221 | 0.76 | SLC6A4 (0.53) | DRD2SLC6A4CYP2D6SLC6A3KMT2A | |
| SCHEMBL10281564 | 0.75 | CYP2D6 (0.58) | DRD2SLC6A4OPRM1CYP2D6CACNA1F | |
| SCHEMBL904826 | 0.75 | HTR2A (0.58) | DRD2SLC6A4OPRM1CYP2D6CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |