Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 7/20 | 0.34 |
| ▸ | SYK | P43405 | 7/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.34 |
| ▸ | GSK3A | P49840 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844349 | 0.86 | KDM4E (0.37) | LMNAMAPTMTNR1BL3MBTL1KDM4E | |
| SCHEMBL203539 | 0.82 | MEN1 (0.37) | SRCMAPK14GSK3AMAPTRXFP1 | |
| SCHEMBL29393804 | 0.82 | MEN1 (0.37) | SRCMAPK14GSK3AMAPTRXFP1 | |
| SCHEMBL203541 | 0.81 | SRC (0.38) | SRCSYKMAPK14GSK3AMAPT | |
| SCHEMBL203536 | 0.80 | MAPT (0.47) | LMNAMAPTMTNR1BNPSR1L3MBTL1 | |
| SCHEMBL29358900 | 0.80 | MAPT (0.47) | LMNAMAPTMTNR1BNPSR1L3MBTL1 | |
| SCHEMBL28691194 | 0.80 | MAPT (0.47) | LMNAMAPTMTNR1BNPSR1L3MBTL1 | |
| SCHEMBL203538 | 0.79 | LMNA (0.51) | LMNAMAPTMTNR1BNPSR1L3MBTL1 | |
| SCHEMBL2108015 | 0.78 | SRC (0.36) | SRCLMNAMAPTRXFP1NPSR1 | |
| SCHEMBL2108009 | 0.78 | SRC (0.36) | SRCLMNAMAPTRXFP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713485-A1 | THIOCARBAMOYL COMPOUNDS | BAYER AG (DE) | 1996-05-29 | — | — | EP | disclosed |
| WO-1995026962-A1 | THIAZOLYLPYRAZOLINONES AND THEIR USE FOR PROTECTING TECHNICAL MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-12 | — | — | WO | disclosed |
| WO-1995004722-A1 | THIOCARBAMOYL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-02-16 | — | — | WO | disclosed |