Sugi Predict

Sugi Predict / Compounds / SCHEMBL203538

SCHEMBL203538

SCHEMBL203538

CCOc1cccc(Oc2ccccc2C(C(=O)O)=C(C)OC)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.51
▸ MAPT P10636 3/20 0.51
▸ MTNR1B P49286 2/20 0.47
▸ L3MBTL1 Q9Y468 4/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ KDM4E B2RXH2 4/20 0.43
▸ POLB P06746 1/20 0.43
▸ LTB4R Q15722 1/20 0.43
▸ LTB4R2 Q9NPC1 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ ACACB O00763 1/20 0.42
▸ ACACA Q13085 1/20 0.42
▸ HTR1D P28221 1/20 0.42
▸ HTR1B P28222 1/20 0.42
▸ NPC1 O15118 1/20 0.42
▸ TP53 P04637 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ GAA P10253 1/20 0.41
▸ RAF1 P04049 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8603089 0.92 LMNA (0.47) LMNAMAPTMTNR1BL3MBTL1KDM4E
SCHEMBL204217 0.92 LMNA (0.47) LMNAMAPTMTNR1BL3MBTL1KDM4E
SCHEMBL203537 0.89 LMNA (0.54) LMNAMAPTMTNR1BL3MBTL1MAPK1
SCHEMBL202626 0.88 KDM4E (0.57) MTNR1BKDM4EPOLBNPC1TP53
SCHEMBL205379 0.85 MEN1 (0.49) MAPTMTNR1BMAPK1KDM4EPOLB
SCHEMBL203718 0.85 CTNNB1 (0.54) LMNAMAPTL3MBTL1KDM4ENPSR1
SCHEMBL204355 0.84 L3MBTL1 (0.44) LMNAMTNR1BL3MBTL1KDM4EPOLB
SCHEMBL203989 0.84 KDM4E (0.44) MAPTMTNR1BKDM4EPOLBNPSR1
SCHEMBL9155384 0.83 SIRT2 (0.47) MAPTMTNR1BMAPK1KDM4EPOLB
SCHEMBL204616 0.82 ALDH1A1 (0.40) MTNR1BMAPK1KDM4EPOLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 — — US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 — — US disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 — — US disclosed
EP-2670239-B1 FORMULATION FOR THE ANTIMICROBIAL AND FUNGICIDAL TREATMENT OF POLYMERIC MATERIALS, IN PARTICULAR OF PAINTS AND COATINGS SANITIZED AG (CH) 2015-08-12 — — EP disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 — — US disclosed
US-8871277-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2014-10-28 — — US disclosed
WO-2014102228-A1 FORMULATION FOR THE ANTIMICROBIAL TREATMENT OF POLYMER COMPOSITIONS SANITIZED AG (CH) 2014-07-03 — — WO disclosed
EP-2749167-A1 Formulation for the antimicrobial treatment of polyvinyl chloride compositions Sanitized AG (CH) 2014-07-02 — — EP disclosed
EP-2670239-A1 FORMULATION FOR THE ANTIMICROBIAL AND FUNGICIDAL TREATMENT OF POLYMERIC MATERIALS, IN PARTICULAR OF PAINTS AND COATINGS Sanitized AG (CH) 2013-12-11 — — EP disclosed
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF AVENTIS AGRICULTURE (FR) 2013-12-05 — — US disclosed
EP-0730517-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AG (DE) 1996-09-11 — — EP disclosed
WO-1996025044-A1 S-ARYL CYANIMIDOTHIO COMPOUNDS FOR MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1996-08-22 — — WO disclosed
EP-0726710-A1 STABILISATION OF IODINE COMPOUNDS USING INORGANIC SUPPORTING MATERIALS FOR USE IN MATERIAL PROTECTION BAYER AG (DE) 1996-08-21 — — EP disclosed
WO-1996010915-A1 INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-04-18 — — WO disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 — — EP disclosed
WO-1995034204-A1 BACTERICIDE THIADIAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1995-12-21 — — WO disclosed
WO-1995014558-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 — — WO disclosed
WO-1995012315-A1 STABILISATION OF IODINE COMPOUNDS USING INORGANIC SUPPORTING MATERIALS FOR USE IN MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1995-05-11 — — WO disclosed
WO-1995011786-A1 TIMBER PROTECTING MEDIUM CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-05-04 — — WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 LMNA 4449/4885MAPT 3249/4885MTNR1B 1812/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 LMNA 2814/4885MAPT 3711/4885MTNR1B 1292/4885
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 LMNA 4191/4885MAPT 4885/4885MTNR1B 510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.