Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.44 |
| ▸ | PTGIR | P43119 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858414 | 0.89 | TBXAS1 (0.59) | TBXAS1KDM4CPTGIRHPGDLMNA | |
| SCHEMBL9049997 | 0.84 | PTGIR (0.45) | TBXAS1KDM4CPTGIRSIGMAR1 | |
| SCHEMBL9567997 | 0.82 | HPGD (0.48) | TBXAS1KDM4CHPGDLMNAHTT | |
| SCHEMBL9051195 | 0.77 | TBXAS1 (0.44) | TBXAS1KDM4CPTGIR | |
| SCHEMBL9048210 | 0.75 | PTGIR (0.53) | TBXAS1KDM4CPTGIRSIGMAR1 | |
| SCHEMBL8858624 | 0.75 | TBXAS1 (0.59) | TBXAS1KDM4CPTGIR | |
| SCHEMBL9051694 | 0.74 | PTGIR (0.52) | KDM4CPTGIRSIGMAR1 | |
| SCHEMBL9048346 | 0.74 | PTGIR (0.52) | PTGIRSIGMAR1 | |
| SCHEMBL8858663 | 0.74 | TBXAS1 (0.57) | TBXAS1KDM4CPTGIRSIGMAR1 | |
| SCHEMBL9047809 | 0.73 | TBXAS1 (0.43) | TBXAS1KDM4CPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |