Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 6/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858440 | 0.88 | PTGIR (0.60) | PTGIRTBXAS1KDM4CSIGMAR1HTR1A | |
| SCHEMBL9048665 | 0.84 | TBXAS1 (0.46) | PTGIRTBXAS1KDM4CSIGMAR1 | |
| SCHEMBL9045227 | 0.78 | TBXAS1 (0.47) | PTGIRTBXAS1KDM4CSIGMAR1 | |
| SCHEMBL9047809 | 0.77 | TBXAS1 (0.43) | PTGIRTBXAS1KDM4C | |
| SCHEMBL9427295 | 0.77 | TBXAS1 (0.43) | PTGIRTBXAS1KDM4C | |
| SCHEMBL9050249 | 0.75 | TBXAS1 (0.42) | PTGIRTBXAS1KDM4C | |
| SCHEMBL9427260 | 0.75 | PTGIR (0.76) | PTGIRTBXAS1KDM4CSIGMAR1 | |
| SCHEMBL9048486 | 0.74 | PTGIR (0.55) | PTGIRTBXAS1KDM4CSIGMAR1 | |
| SCHEMBL8858414 | 0.73 | TBXAS1 (0.59) | PTGIRTBXAS1KDM4C | |
| SCHEMBL9050869 | 0.72 | PTGIR (0.53) | PTGIRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |