Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.40 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048705 | 1.00 | GLO1 (0.67) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL28285733 | 1.00 | GLO1 (0.67) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL214459 | 0.89 | NPSR1 (0.56) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL11656177 | 0.84 | GLO1 (0.47) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL11656175 | 0.84 | GLO1 (0.47) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL23394794 | 0.83 | NPSR1 (0.50) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL296438 | 0.83 | NPSR1 (0.50) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL4197379 | 0.83 | GLO1 (0.67) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL1186674 | 0.83 | GLO1 (0.67) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL1186672 | 0.83 | GLO1 (0.67) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379806-B1 | Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines | MITSUI PETROCHEMICAL IND (JP) | 1996-04-10 | — | — | EP | disclosed |
| EP-0612746-A1 | Pyrimidines and their pharmaceutical acceptable salts and their use as medicines | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5264435-A | Treatment of neurological diseases | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5147876-A | Nervous system disorders | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| US-4104049-A | Chlorine-substituted vinylaminobenzoic acid compounds and plant growth regulant compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |