Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567994 | 0.92 | PDPK1 (0.43) | HTTMAPK1MAPK14RAB9AMEN1 | |
| SCHEMBL9567983 | 0.86 | MAPK1 (0.44) | HTTMAPK1MAPK14RAB9AMEN1 | |
| SCHEMBL9567991 | 0.78 | PIN1 (0.40) | MAPK1MAPK14MEN1KMT2ATAS1R3 | |
| SCHEMBL9048717 | 0.77 | PTGIR (0.50) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9515277 | 0.74 | IDO1 (0.44) | HTTMAPK1MAPK14RAB9AMEN1 | |
| SCHEMBL9568069 | 0.73 | MTNR1A (0.44) | — | |
| SCHEMBL3394130 | 0.72 | PDPK1 (0.44) | HTTMAPK1MAPK14RAB9AMEN1 | |
| SCHEMBL14815564 | 0.70 | IDO1 (0.46) | HTTMAPK1MAPK14RAB9ALMNA | |
| SCHEMBL13569354 | 0.70 | HTT (0.64) | HTTMEN1KMT2ALMNATAS1R3 | |
| SCHEMBL20706323 | 0.70 | IDO1 (0.49) | HTTMAPK1MAPK14LMNATAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |