Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 6/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050478 | 0.91 | PTGIR (0.39) | PTGIRDRD4ACHE | |
| SCHEMBL9048942 | 0.86 | PTGIR (0.55) | PTGIR | |
| SCHEMBL9048583 | 0.83 | PTGIR (0.45) | PTGIR | |
| SCHEMBL9427080 | 0.82 | PTGIR (0.39) | PTGIRDRD4ACHE | |
| SCHEMBL9047991 | 0.81 | PTGIR (0.38) | PTGIRDRD4ACHE | |
| SCHEMBL9048929 | 0.80 | TDP1 (0.36) | PTGIRTDP1 | |
| SCHEMBL9046455 | 0.79 | TBXAS1 (0.51) | PTGIR | |
| SCHEMBL9427236 | 0.78 | PTGIR (0.43) | PTGIRACHE | |
| SCHEMBL9050662 | 0.78 | PTGIR (0.47) | PTGIR | |
| SCHEMBL9427127 | 0.78 | PTGIR (0.43) | PTGIRDRD4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |