Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.35 |
| ▸ | PTGIR | P43119 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050469 | 0.90 | KMT2A (0.36) | TDP1TRPM8PTGIRKMT2AALDH1A1 | |
| SCHEMBL9048581 | 0.82 | PTGIR (0.39) | TRPM8PTGIR | |
| SCHEMBL9567968 | 0.80 | TRPM8 (0.49) | TDP1TRPM8ALDH1A1 | |
| SCHEMBL9048942 | 0.80 | PTGIR (0.55) | PTGIR | |
| SCHEMBL9048934 | 0.80 | PTGIR (0.39) | TDP1PTGIR | |
| SCHEMBL9047990 | 0.79 | EPHX1 (0.36) | TRPM8 | |
| SCHEMBL9427074 | 0.79 | TRPM8 (0.35) | TRPM8PTGIRALDH1A1 | |
| SCHEMBL9427232 | 0.77 | PTGIR (0.36) | TDP1TRPM8PTGIRKMT2AALDH1A1 | |
| SCHEMBL9049782 | 0.77 | PTGIR (0.38) | TRPM8PTGIRKMT2A | |
| SCHEMBL9048469 | 0.75 | TRPM8 (0.34) | TDP1TRPM8ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |