Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.41 |
| ▸ | ACHE | P22303 | 8/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047724 | 0.94 | PTGIR (0.48) | PTGIR | |
| SCHEMBL9048983 | 0.86 | PTGIR (0.57) | PTGIR | |
| SCHEMBL9051610 | 0.85 | SLC6A4 (0.40) | PTGIRACHEMAOAMAOB | |
| SCHEMBL9051694 | 0.84 | PTGIR (0.52) | PTGIR | |
| SCHEMBL9048863 | 0.82 | PTGIR (0.51) | PTGIRCHRM2CHRM1CHRM3 | |
| SCHEMBL9048971 | 0.81 | PTGIR (0.37) | PTGIR | |
| SCHEMBL9046170 | 0.80 | PTGIR (0.44) | PTGIRACHE | |
| SCHEMBL9047729 | 0.80 | PTGIR (0.66) | PTGIR | |
| SCHEMBL9050616 | 0.80 | PTGIR (0.46) | PTGIR | |
| SCHEMBL9567993 | 0.79 | PRMT5 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |