Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050616 | 0.94 | PTGIR (0.46) | SLC6A4SLC6A3PTGIRKMT2AL3MBTL1 | |
| SCHEMBL9048978 | 0.85 | PTGIR (0.41) | PTGIRACHEMAOAMAOB | |
| SCHEMBL9051611 | 0.85 | PTGIR (0.54) | PTGIR | |
| SCHEMBL9048210 | 0.84 | PTGIR (0.53) | PTGIR | |
| SCHEMBL9048346 | 0.82 | PTGIR (0.52) | PTGIR | |
| SCHEMBL9048138 | 0.81 | PTGIR (0.52) | SLC6A4SLC6A3PTGIRALDH1A1 | |
| SCHEMBL9047724 | 0.80 | PTGIR (0.48) | PTGIR | |
| SCHEMBL9427064 | 0.80 | LMNA (0.45) | LMNAPTGIR | |
| SCHEMBL9050622 | 0.79 | PTGIR (0.62) | PTGIR | |
| SCHEMBL9051607 | 0.79 | KMT2A (0.43) | SLC6A4SLC6A3LMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |