Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | UGCG | Q16739 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567986 | 0.93 | UGCG (0.50) | PRMT5WDR77MTNR1BUGCGTRPM8 | |
| SCHEMBL9568047 | 0.81 | TRPV1 (0.44) | UGCGHTR6 | |
| SCHEMBL9048971 | 0.81 | PTGIR (0.37) | PRMT5WDR77MTNR1BUGCGPPARD | |
| SCHEMBL9567998 | 0.81 | PRMT5 (0.49) | PRMT5WDR77MTNR1BUGCGMTNR1A | |
| SCHEMBL9567956 | 0.80 | UGCG (0.48) | PRMT5WDR77MTNR1BUGCGMTNR1A | |
| SCHEMBL9048978 | 0.79 | PTGIR (0.41) | — | |
| SCHEMBL9048983 | 0.79 | PTGIR (0.57) | — | |
| SCHEMBL9047720 | 0.77 | PTGIR (0.43) | UGCG | |
| SCHEMBL19985007 | 0.76 | PRMT5 (0.51) | PRMT5WDR77MTNR1BMTNR1AFFAR1 | |
| SCHEMBL9047724 | 0.75 | PTGIR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |