Morpholine

Morpholine

SCHEMBL9049013

C1COCCN1.c1cc[nH]c1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
KDM4E B2RXH2 1/20 0.58
GAA P10253 1/20 0.58
CYP2C9 P11712 1/20 0.58
APEX1 P27695 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL28786038 0.89 MEN1 (0.46) MEN1KMT2AKDM4EGAACYP2C9
Oxazolidine SCHEMBL27934362 0.84 MEN1 (0.39) MEN1KMT2AKDM4EGAACYP2C9
Dioxane SCHEMBL28087350 0.82 TTR (0.43) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL3664363 0.82 MEN1 (0.73) MEN1KMT2AKDM4EGAACYP2C9
Piperazine SCHEMBL27889328 0.82 HIF1A (0.43) MEN1KMT2AKDM4EGAACYP2C9
Pyrrole SCHEMBL28636726 0.82
Piperazine SCHEMBL20360553 0.78 HIF1A (0.46) KDM4EGAACYP2C9
Piperazine SCHEMBL28257898 0.78 HIF1A (0.46) KDM4EGAACYP2C9
Pyrrole SCHEMBL18339868 0.78
Morpholine SCHEMBL18434 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110087466-A ACTIVE COMPOUND COMBINATIONS 拜耳作物科学股份公司 2019-08-02 CN claimed
CN-107105646-A Use of surface-reacted calcium carbonate as a carrier for agrochemical compounds OMYA国际股份公司 2017-08-29 CN claimed
CN-101720771-A Wettable powder compounded by pyrimorph and mancozeb and preparation method thereof JIANGSU FREY AGROCHEMICALS CO 2010-06-09 CN claimed
EP-0381422-B1 Tetrahydrobenzimidazole derivatives YAMANOUCHI PHARMA CO LTD (JP) 1996-10-23 EP claimed
WO-2021114091-A1 HOMOGENEOUS CATALYST AND HETEROGENEOUS CATALYST BASED ON IONIC LIQUID, AND PREPARATION METHOD THEREFOR AND USE THEREOF 沈阳化工大学 2021-06-17 WO disclosed
CN-111804331-A Homogeneous catalyst and heterogeneous catalyst based on ionic liquid, and preparation method and application thereof 沈阳化工大学 2020-10-23 CN disclosed
CN-108359175-A A kind of preparation method of slow-release volatile rust prevention stretched polypropene film 江阴通利光电科技有限公司 2018-08-03 CN disclosed
CN-108347877-A Stable inoculation compositions and its production method 诺维信生物农业公司 2018-07-31 CN disclosed
CN-108024545-A Stable inoculation compositions and its production method 诺维信生物农业公司 2018-05-11 CN disclosed
CN-106135290-A Amide containing class, dinitroaniline, dithiocarbamate antibacterial and the compositions of biocontrol microorganisms, preparation and application 中国烟草总公司郑州烟草研究院 2016-11-23 CN disclosed
CN-106035383-A Bactericide composition containing chemical bactericides and biocontrol bacterium, preparation and application of bactericide composition or preparation 中国烟草总公司郑州烟草研究院 2016-10-26 CN disclosed
CN-102715172-A Application of dibenzyl acryloyl aminated compound as agricultural bactericide SINOCHEM CORP 2012-10-10 CN disclosed
CN-102549072-A Method for the continuous production of polyester mixtures BASF SE 2012-07-04 CN disclosed
CN-101965845-A Pyrimorph- and cymoxanil-containing fungicide composition SHAANXI TANGPUSEN BIOTECH CO 2011-02-09 CN disclosed
CN-101965844-A Pyrimorph-containing antibacterial composition SHAANXI TANGPUSEN BIOTECH CO 2011-02-09 CN disclosed
CN-1939128-A Agricultural bacteriocide-P3rimorph UNIV CHINA AGRICULTURAL (CN) 2007-04-04 CN disclosed
CN-1441790-A Enhanced propertied pharmaceuticals ROHM & HAAS (US) 2003-09-10 CN disclosed