Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL18339868 | 0.96 | — | — | |
| Pyrrole SCHEMBL29867603 | 0.93 | — | — | |
| Tetrahydrofuran SCHEMBL2148282 | 0.87 | ALDH1A1 (0.50) | ALDH1A1 | |
| Pyrrole SCHEMBL2977186 | 0.87 | — | — | |
| Pyrrole SCHEMBL27352233 | 0.84 | ALDH1A1 (0.47) | ALDH1A1 | |
| Morpholine SCHEMBL9049013 | 0.82 | MEN1 (0.58) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Pyrrole SCHEMBL28200279 | 0.82 | ALDH1A1 (0.44) | ALDH1A1 | |
| Pyrrole SCHEMBL4758278 | 0.80 | — | — | |
| Pyrrole SCHEMBL29229959 | 0.80 | — | — | |
| Pyrrole SCHEMBL27477447 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103249732-B | The bacterial topoisomerase II of suppression 2-ethyl carbamyl amino-1,3-benzothiazole-5-base | 生物区欧洲有限公司 | 2016-08-10 | — | — | CN | disclosed |