Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049638 | 0.86 | MAOB (0.56) | MAOBBCHEACHEMAOA | |
| SCHEMBL9063372 | 0.85 | MAOB (0.63) | MAOBBCHEACHE | |
| SCHEMBL9051174 | 0.85 | MAOB (0.63) | MAOBBCHEACHE | |
| SCHEMBL9048736 | 0.84 | MAOB (0.54) | MAOBBCHEACHEMAOA | |
| SCHEMBL9048953 | 0.84 | MAOB (0.62) | MAOBBCHEACHE | |
| SCHEMBL9051412 | 0.83 | PARK7 (0.63) | MAOBBCHEACHEMAOA | |
| SCHEMBL4500323 | 0.81 | MAOB (0.51) | MAOBBCHEACHEMAOA | |
| SCHEMBL9047059 | 0.80 | MAOB (0.50) | MAOBBCHEACHEMAOA | |
| SCHEMBL9056094 | 0.79 | MAOB (0.48) | MAOBBCHEACHEMAOA | |
| SCHEMBL578360 | 0.76 | MEN1 (0.57) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703901-A1 | 1-SUBSTITUTED ISATIN AND OXINDOLE DERIVATIVES AS INHIBITORS OF ACETYLCHOLINESTERASE | Astra Aktiebolag (SE) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029272-A1 | 1-SUBSTITUTED ISATIN AND OXINDOLE DERIVATIVES AS INHIBITORS OF ACETYLCHOLINESTERASE | ASTRA AKTIEBOLAG (SE) | 1994-12-22 | — | — | WO | disclosed |