Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3189044 | 0.83 | MAPT (0.40) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9263418 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9272658 | 0.82 | LMNA (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL1349347 | 0.81 | MGAM (0.47) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4671913 | 0.81 | MAPT (0.42) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL5502158 | 0.80 | MEN1 (0.43) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL7004770 | 0.79 | MAPT (0.37) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL7005285 | 0.78 | MAPT (0.37) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9046771 | 0.78 | KDM4E (0.41) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL1348394 | 0.75 | GAA (0.47) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700912-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |