Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047848 | 0.94 | PTGIR (0.43) | PTGIRLMNAGAA | |
| SCHEMBL8858455 | 0.80 | PTGIR (0.61) | PTGIR | |
| SCHEMBL9048927 | 0.80 | PTGIR (0.43) | PTGIRLMNAGAA | |
| SCHEMBL9567959 | 0.75 | HTT (0.46) | PTGIRPIN1LMNA | |
| SCHEMBL8858680 | 0.74 | PTGIR (0.67) | PTGIR | |
| SCHEMBL9568056 | 0.71 | PTGIR (0.40) | PTGIRLMNAGAA | |
| SCHEMBL9427205 | 0.71 | PTGIR (0.69) | PTGIR | |
| SCHEMBL9427118 | 0.70 | PTGIR (0.61) | PTGIR | |
| SCHEMBL9427356 | 0.67 | PTGIR (0.55) | PTGIR | |
| SCHEMBL9050245 | 0.65 | PTGIR (0.60) | PTGIRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |