Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047848 | 0.87 | PTGIR (0.43) | PTGIRLMNAGAATAS1R3TAS1R1 | |
| SCHEMBL9049152 | 0.80 | PTGIR (0.38) | PTGIRLMNAGAA | |
| SCHEMBL9427205 | 0.79 | PTGIR (0.69) | PTGIRKDM4E | |
| SCHEMBL9049008 | 0.79 | LMNA (0.48) | DRD4LMNAGAASLC6A5ALDH1A1 | |
| SCHEMBL9046465 | 0.78 | PRMT5 (0.41) | DRD4SLC6A5P2RX7KDM4E | |
| SCHEMBL9048933 | 0.78 | PTGIR (0.52) | PTGIRDRD4 | |
| SCHEMBL9046416 | 0.78 | PTGIR (0.70) | PTGIRDRD4 | |
| SCHEMBL9427118 | 0.78 | PTGIR (0.61) | PTGIRKDM4E | |
| SCHEMBL9050555 | 0.76 | NPSR1 (0.47) | KDM4EALDH1A1 | |
| SCHEMBL9046164 | 0.76 | PTGIR (0.37) | PTGIRDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |