Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 18/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047722 | 0.91 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL7680745 | 0.81 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL7681958 | 0.79 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL9046216 | 0.78 | CRHR1 (0.63) | CRHR1 | |
| SCHEMBL9044173 | 0.77 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL9045095 | 0.77 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL7685166 | 0.76 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL9047025 | 0.76 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL9047737 | 0.76 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL9045279 | 0.76 | CRHR1 (0.57) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | claimed |
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |