Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 12/20 | 0.46 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045095 | 0.88 | CRHR1 (0.59) | CRHR1NAPEPLDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL7678394 | 0.84 | CRHR1 (0.63) | CRHR1 | |
| SCHEMBL9047722 | 0.82 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL8047865 | 0.79 | CRHR1 (0.55) | CRHR1NAPEPLDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL9048414 | 0.78 | CRHR1 (0.48) | CRHR1NAPEPLDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL9049227 | 0.77 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL7678178 | 0.77 | CRHR1 (0.57) | CRHR1MEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9046910 | 0.76 | CRHR1 (0.72) | CRHR1MEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7687345 | 0.75 | CRHR1 (0.63) | CRHR1MEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9047393 | 0.74 | CRHR1 (0.55) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |