Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049251 | 1.00 | CCR5 (0.37) | CCR5ATMCNR2HSD11B1ALDH1A1 | |
| SCHEMBL9049261 | 1.00 | CCR5 (0.37) | CCR5ATMCNR2HSD11B1ALDH1A1 | |
| SCHEMBL9049245 | 1.00 | CCR5 (0.37) | CCR5ATMCNR2HSD11B1ALDH1A1 | |
| SCHEMBL9049260 | 1.00 | CCR5 (0.37) | CCR5ATMCNR2HSD11B1ALDH1A1 | |
| SCHEMBL9047580 | 0.88 | NPC1 (0.41) | CCR5ATMALDH1A1POLB | |
| SCHEMBL9047592 | 0.88 | NPC1 (0.41) | CCR5ATMALDH1A1POLB | |
| SCHEMBL9047586 | 0.88 | NPC1 (0.41) | CCR5ATMALDH1A1POLB | |
| SCHEMBL9047597 | 0.88 | NPC1 (0.41) | CCR5ATMALDH1A1POLB | |
| SCHEMBL9047609 | 0.88 | NPC1 (0.41) | CCR5ATMALDH1A1POLB | |
| SCHEMBL9048285 | 0.85 | CCR5 (0.37) | CCR5CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |